4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione → HCID 178493747, compound

Participants

Reaction Steps

A mixture of 2-aminomethyl-5-methoxy-pyridin-4-ol (116 mg, 0.75 mmole), 4 mL of N,N-dimethylformamide and 4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione (247 mg, 0.75 mmole) is added and the reaction mixture stirred for one hour. The reaction mixture is evaporated to dryness and treated with acetonitrile, the solid filtered and dried to give a pink solid, 293 mg, (87%); MS (ES+): m/z 451.9 (M+H).

Provenance & Evidence