Methyl diethylphosphonoacetate → (E)-1-(7-methoxycarbonyl-5,5-dimethyl-6-heptenyl)imidazole

HRID 223680Notes

Reaction equation

[CH:1]([C:3]([CH3:14])([CH3:13])[CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)=O.[CH3:15][O:16][C:17]([CH2:19]P(=O)(OCC)OCC)=[O:18]>>[CH3:15][O:16][C:17](/[CH:19]=[CH:1]/[C:3]([CH3:14])([CH3:13])[CH2:4][CH2:5][CH2:6][CH2:7][N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)=[O:18]

Participants

Reactant 2

HCID 66113Methyl diethylphosphonoacetate

HCID 12870476HCID 12870476, compound

Product 1

HCID 20521646(E)-1-(7-methoxycarbonyl-5,5-dimethyl-6-heptenyl)imidazole

Procedure

By the proceeding as described in Example 1 but utilizing 1-(5-formyl-5-methylhexyl)imidazole and diethyl methoxycarbonylmethylphosphonate, there was obtained the title compound having the following physical characteristic in 66% yields:

Sources & evidence

ORD record: ord-f0216efe6c954691a8635a8fb1ce3f91
Source dataset: uspto-grants-1982_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04355170

Reaction notes

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