4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione → HCID 178493748, compound

Participants

Reaction Steps

2-Aminomethyl-5-methoxy-pyrimidin-4-ol (10 mg, 0.064 mmol) and 6-iodo-4-methoxymethylene-4H-isoquinoline-1,3-dione (50 mg, 0.15 mmol) in N,N-dimethylformamide (3 mL) is stirred at room temperature for 1 hour. The N,N-dimethylformamide is then removed and residue purified to provide the title compound (10 mg, 34%). MS (ESI): 453 (M+1)+1.

Provenance & Evidence