HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione → HCID 178518365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-methoxymethylene-6-iodo-4H-isoquinoline-1,3-dione | HCID 68691019 | — |
| Reactant | HCID 135922726 | HCID 135922726 | — |
| Reactant | HCID 178518360 | HCID 178518360 | — |
| Product | HCID 178518365 | HCID 178518365 | 40% |
Reaction Steps
Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione, the title compound is prepared from 6-iodo-4-methoxymethylene-4H-isoquinoline-1,3-dione (50 mg, 0.15 mmol) and 5-Aminomethyl-2-pyridin-2-yl-phenol (40 mg, 0.20 mmol) in 40% yield: MS (ESI): 498.1 (M+1)+1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-9e7eabc1d7f54f45a25fb901bc99a4ff |
| Source note | uspto-grants-2010_05 |