HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminomethyl-2-furan-3-yl-phenol → HCID 178440610, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminomethyl-2-furan-3-yl-phenol | HCID 42625670 | — |
| Reactant | 6-tert-Butyl-4-methoxymethylene-4H-isoquinoline-1,3-dione | HCID 68692567 | — |
| Reactant | HCID 178518360 | HCID 178518360 | — |
| Product | HCID 178440610 | HCID 178440610 | 50% |
Reaction Steps
Following the same procedure for the preparation of 4-{[(2-Hydroxy-biphenyl-4-ylmethyl)-amino]-methylene}-6-iodo-4H-isoquinoline-1,3-dione, the title compound (purified through chromatography) is prepared from 6-tert-Butyl-4-methoxymethylene-4H-isoquinoline-1,3-dione (˜15 mg, 0.058 mmol) and 5-Aminomethyl-2-furan-3-yl-phenol (40 mg, 0.21 mmol) in 50% yield: MS (ESI): 415.1 (M−1)−1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07713994B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-b7b8023d3fc242a8accfc9bca240411b |
| Source note | uspto-grants-2010_05 |