Sodium Hydroxide → HCID 54457653, compound

HRID 223690Notes

Reaction equation

HRID 223690 reaction equation
C[O:2][C:3](=[O:33])[C@H:4]([CH2:23][C:24]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[NH:26][CH:25]=1)[NH:5][C:6](=[O:22])[C@H:7]([C:18]([CH3:21])([CH3:20])[CH3:19])[NH:8][C:9](=[O:17])[CH:10]([CH3:16])[CH2:11][S:12]C(=O)C.[OH-].[Na+]>C(O)C>[SH:12][CH2:11][CH:10]([CH3:16])[C:9]([NH:8][C@H:7]([C:6]([NH:5][C@H:4]([C:3]([OH:33])=[O:2])[CH2:23][C:24]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[NH:26][CH:25]=1)=[O:22])[C:18]([CH3:21])([CH3:20])[CH3:19])=[O:17]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 57059118HCID 57059118, compound

Product 1

HCID 54457653HCID 54457653, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound is prepared using the previously described procedures and the following reagants: 0.90 g (1.89 mmoles) of N-(S-acetyl-β-mercaptoisobutyroyl)-3-methylvalyl-tryptophan methyl ester, 8 ml of 95 percent ethanol, 4.0 ml of 1 N NaOH. Chromatographed yield is 0.54 grams (63 percent). Analysis calculated for C21H29N3O4S: C, 60.12; H, 6.97; N, 10.02; S, 7.64. Found: C, 60.27; H, 7.14; N, 9.42; S, 7.25.

Workup

  1. customChromatographed yield is 0.54 grams (63 percent)

Sources & evidence

ORD record
ord-83d0497503204b9b85b9aacbb75140b7
Source dataset
uspto-grants-1982_10
Patent number
US04356118

Reaction notes

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