4-(4-Nitrophenoxy)-1,1'-biphenyl → 4-(4-Phenylphenoxy)aniline

Participants

Reaction Steps

The nitro intermediate (10 mmol) obtained above was dissolved in EtOAc (40 mL) and hydrogenated in the presence of 10% Pd/C (360 mg) until completion, as indicated by TLC or HPLC. The reaction mixture was then filtered to remove the catalyst. The solvent was removed in vacuo to afford the desired 4-(biphenyl-4-oxy)aniline, which was used directly for further transformation without further purification.

Provenance & Evidence