Ammonia → HCID 22817577, compound

HRID 223723Notes

Reaction equation

C([S:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:16][C:15]([CH2:18][CH3:19])([OH:17])[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.N>>[CH2:18]([C:15]1([OH:17])[CH2:16][N:9]([C:7](=[O:8])[CH2:6][CH2:5][SH:4])[C@H:10]([C:11]([OH:13])=[O:12])[CH2:14]1)[CH3:19]

Participants

Reactant 2

HCID 222Ammonia

HCID 54130906HCID 54130906, compound

Product 1

HCID 22817577HCID 22817577, compound

Procedure

The product from part (b) is treated with concentrated ammonia according to the procedure of Example 2 to yield 4-ethyl-4-hydroxy-1-(3-mercapto-1-oxopropyl)-L-proline.

Sources & evidence

ORD record: ord-2261cd370f8a4197b6d33b696194608d
Source dataset: uspto-grants-1982_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04356182

Reaction notes

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