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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 223726Generated: October 30, 2026

Ammonia → 4-hydroxy-4-[(4-methyl)phenyl]-1-(4-mercapto-1-oxobutyl)-L-proline

https://huagongshe.com/reaction/223726

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
Reactant1-[4-(Acetylthio)-1-oxobutyl]-4-hydroxy-4-[(4-methyl)phenyl]-L-prolineHCID 22817492—
Product4-hydroxy-4-[(4-methyl)phenyl]-1-(4-mercapto-1-oxobutyl)-L-prolineHCID 22817579—

Reaction Steps

The product from part (b) is treated with concentrated ammonia according to the procedure of Example 2 to yield 4-hydroxy-4-[(4-methyl)phenyl]-1-(4-mercapto-1-oxobutyl)-L-proline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04356182
Source datasetuspto-grants-1982_10
ORD IDord-dc31a2e7493c404d8b23f4889597b135
Source noteuspto-grants-1982_10