Ammonia → HCID 57305396, compound

HRID 223734Notes

Reaction equation

HRID 223734 reaction equation
C([S:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:13][C:12]([CH2:14][C:15]2[S:16][CH:17]=[CH:18][CH:19]=2)=[CH:11][C@H:10]1[C:20]([OH:22])=[O:21])=[O:8])(=O)C.N>>[SH:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:13][C:12]([CH2:14][C:15]2[S:16][CH:17]=[CH:18][CH:19]=2)=[CH:11][C@H:10]1[C:20]([OH:22])=[O:21])=[O:8]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 22817575HCID 22817575, compound

Product 1

HCID 57305396HCID 57305396, compound

Procedure

The product from part (b) is treated with concentrated ammonia according to the procedure of Example 4 to yield (2S)-2,5-dihydro-1-(3-mercapto-1-oxopropyl)-4-[(2-thienyl)methyl]-1H-pyrrole-2-carboxylic acid.

Sources & evidence

ORD record
ord-194d36def3154f77b53ba7bbe052b563
Source dataset
uspto-grants-1982_10
Patent number
US04356182

Reaction notes

Loading…