HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(Acetylthio)-1-oxoethyl]-4-[(2-furyl)methyl]-4-hydroxy-L-proline → 4-[(2-furyl)methyl]-4-hydroxy-L-proline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(Acetylthio)-1-oxoethyl]-4-[(2-furyl)methyl]-4-hydroxy-L-proline | HCID 54147793 | — |
| Reactant | N-carbobenzyloxy-4-[(2-furyl)methyl]-4-hydroxy-L-proline | HCID 54161613 | — |
| Product | 4-[(2-furyl)methyl]-4-hydroxy-L-proline | HCID 54134392 | — |
Reaction Steps
The N-carbobenzyloxy-4-[(2-furyl)methyl]-4-hydroxy-L-proline from part (a) is hydrogenated according to the procedure of Example 1 (b) to yield 4-[(2-furyl)methyl]-4-hydroxy-L-proline. This amino acid is reacted with 2-acetylthioacetyl chloride according to the procedure of Example 1 (c) to yield 1-[2-(acetylthio)-1-oxoethyl]-4-[(2-furyl)methyl]-4-hydroxy-L-proline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04356182 |
| Source dataset | uspto-grants-1982_10 |
| ORD ID | ord-6f3d0f8ebbf640878818e697dc27e1b2 |
| Source note | uspto-grants-1982_10 |