Triphenylphosphine → 3-Phenylpropyl triphenylphosphonium bromide

Participants

Reaction Steps

Triphenylphosphine (2.364 g, 9.00 mmol) was added to (3-bromo-propyl)-benzene (1.552 g, 8.00 mmol) in 35 mL toluene in a 100-mL round-bottom flask. The mixture was heated to reflux under argon and stirred 48 h, then concentrated in vacuo. The resulting white amorphous solid was triturated with ether (3×20 mL) to yield 1.984 g (55%) white solid. 1H NMR (CDCl3, 300 MHz) δ7.66-7.83 (m, 15H), 7.19-7.27 (m, 5H), 3.92-4.02 (m, 2H), 3.06 (t, J=7.2 Hz, 2H), 1.92-2.00 (m, 2H).

Provenance & Evidence