Isoamyl Nitrite → HCID 59302559, compound

Participants

Reaction Steps

The product from step b) (256 mg, 0.69 mmol) was stirred in TFA (2 mL) for 30 minutes. The reaction was concentrated and dissolved in EtOH (5 mL). Isoamyl nitrite (140 μL, 1.04 mmol) and Cu(OAc)2 (188 mg, 1.04 mmol) were added to the solution and the reaction was stirred at room temperature overnight. The reaction was filtered through a silica plug and purified by silica gel chromatography (EtOAc/Hex-gradient) to give 17 mg of the subtitle compound. MS: ESI (positive): 271 (M+H).

Provenance & Evidence