Acetic Acid → HCID 59302552, compound

Participants

Reaction Conditions

Reaction Steps

A solution of the product from example 3, step a) (148 mg, 0.39 mmol) in AcOH (80 μl) and H2O (1.92 ml) was treated with Zn (76 mg, 1.17 mmol) at 105° C. for 4.5 hours. Next, the contents were cooled to 22° C., poured into sat. NaHCO3 (25 ml) and extracted with EtOAc (2×25 ml). The organic layer was dried (MgSO4) and concentrated providing 80 mg (68%) of the subtitle compound, which was used without further purification.

Provenance & Evidence