HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((Pyrrolidine-1-carbonyl)methyl)piperazine → HCID 42643068, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((Pyrrolidine-1-carbonyl)methyl)piperazine | HCID 100614 | — |
| Reactant | [2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid | HCID 677042 | — |
| Product | HCID 42643068 | HCID 42643068 | — |
Reaction Steps
In analogy to example 1.3, [2-(4-chloro-benzoylamino)-thiazol-4-yl]-acetic acid (example 1.2) was coupled with 1-(pyrrolidinocarbonylmethyl)piperazine to give 4-chloro-N-(4-{2-oxo-2-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethyl}-thiazol-2-yl)-benzamide, using general procedure A. Off-white solid. MS 476.1 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07718659B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-aa8910e94ba2454783cf65ef5585befd |
| Source note | uspto-grants-2010_05 |