1-(1-Methyl-4-piperidinyl)piperazine → HCID 42643069, compound

Participants

Role	Name	HCID	Charge
Reactant	1-(1-Methyl-4-piperidinyl)piperazine	HCID 566324	—
Reactant	[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid	HCID 677042	—
Product	HCID 42643069	HCID 42643069	—

Reaction Steps

In analogy to example 1.3, [2-(4-chloro-benzoylamino)-thiazol-4-yl]-acetic acid (example 1.2) was coupled with 1-(N-methylpiperidin-4-yl)piperazine to give 4-chloro-N-(4-{2-[4-(1-methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-thiazol-2-yl)-benzamide, using general procedure C. Off-white solid. MS 462.3 ([M+H]+)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07718659B2
Source dataset	uspto-grants-2010_05
ORD ID	ord-eec9c9952dc24b00b6a1f662a07e1e3c
Source note	uspto-grants-2010_05