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HRID2237663

反应详情

EQUATION

反应方程式

HRID 2237663 的结构方程式

REACTANTS

反应物

2
结构：O=S(=O)(Cl)c1cccc2cccnc12
HCID29220

8-Quinolinesulfonyl chloride

C9H6ClNO2S

结构：CC(C)(C)OC(=O)N1CCN(c2ccc(N)c(NS(=O)(=O)c3ccccc3)c2)CC1
HCID22272479

未命名化合物

PRODUCTS

生成物

1
结构：O=S(=O)(Nc1cc(N2CCNCC2)ccc1NS(=O)(=O)c1cccc2cccnc12)c1ccccc1
HCID10208374

未命名化合物

PROCEDURE

实验过程

N-[2-[(Phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]-8-quinolinesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and 8-quinolinesulfonylchloride (54 mg, 0.239 mmol) according to general method 3 to give 50 mg of a purple solid. MS (posES-FIA) m/z=Found: 524.2; Calcd: 524.13; 1H NMR δ 9.34 (dd, 1H), 8.79 (dd, 1H), 8.37 (dd, 1H), 8.25 (dd, 1H), 7.92 (dd, 1H), 7.73 (t, 1H), 7.57-7.40 (m, 5H), 7.17 (d, 1H), 6.71 (dd, 1H), 6.14 (d, 1H), 3.23-3.08 (m, 8H).