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HRID2237668

反应详情

EQUATION

反应方程式

HRID 2237668 的结构方程式

REACTANTS

反应物

2
反应SMILES：Cc1ccccc1S(=O)(=O)Cl
HCID8623

Toluene-2-sulphonyl chloride

C7H7ClO2S

反应SMILES：CC(C)(C)OC(=O)N1CCN(c2ccc(N)c(NS(=O)(=O)c3ccccc3)c2)CC1
HCID22272479

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cc1ccccc1S(=O)(=O)Nc1ccc(N2CCNCC2)cc1NS(=O)(=O)c1ccccc1
HCID10228032

未命名化合物

PROCEDURE

实验过程

2-Methyl-N-[2-[(phenylsulfonyl)amino]-4-(1-piperazinyl)phenyl]benzenesulfonamide was synthesized from N-{2-amino-5-(4-t-butyloxycarbonyl-piperazinyl)-phenyl}benzenesulfonamide and o-toluenesulfonylchloride (46 mg, 0.239 mmol) according to general method 3 to give before Boc-deprotection 160 mg of a purple solid. MS (posES-FIA) m/z=Found: 487.1; Calcd 487.14; 1H-NMR δ 7.74-7.16 (m, 8H), 6.78-6.52 (m, 4H), 3.27-3.16 (m, 8H), 2.58 (s, 3H).

WORKUP

后处理

  1. customto give before Boc-deprotection 160 mg of a purple solid