HRID2237702

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID29220

8-Quinolinesulfonyl chloride

C9H6ClNO2S

结构：CC(C)(C)OC(=O)N1CCCN(c2ccc(N)c(NS(=O)(=O)c3ccccc3)c2)CC1

HCID22272501

未命名化合物

PRODUCTS

生成物

结构：Cl.O=S(=O)(Nc1cc(N2CCCNCC2)ccc1NS(=O)(=O)c1cccc2cccnc12)c1ccccc1

HCID10120797

未命名化合物

PROCEDURE

实验过程

The compound was synthesized from of N-{2-amino-5-(4-t-butyloxycarbonyl-1,4-diazepan-1-yl)-phenyl}benzenesulfonamide and 8-quinolinesulfonylchloride (61 mg, 0.27 mmol) to give 34 mg of a purple solid. M+ 1 538.2 Calcd 538.15.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c6bc0327a7d2452e96d03195732b2682
来源数据集: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07718650B2
来源说明: uspto-grants-2010_05

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[CH2:14][CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]2)=[CH:4][C:3]=1[NH:22][S:23]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)(=[O:25])=[O:24].[N:32]1[C:41]2[C:36](=[CH:37][CH:38]=[CH:39][C:40]=2[S:42]([Cl:45])(=[O:44])=[O:43])[CH:35]=[CH:34][CH:33]=1>>[ClH:45].[N:8]1([C:5]2[CH:6]=[CH:7][C:2]([NH:1][S:42]([C:40]3[CH:39]=[CH:38][CH:37]=[C:36]4[C:41]=3[N:32]=[CH:33][CH:34]=[CH:35]4)(=[O:44])=[O:43])=[C:3]([NH:22][S:23]([C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)(=[O:25])=[O:24])[CH:4]=2)[CH2:14][CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1