HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-methyl-1-propanol → 2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiazole-5-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-methyl-1-propanol | HCID 11807 | — |
| Reactant | 2-Chloro-1,3-thiazole-5-sulfonyl chloride | HCID 16228943 | — |
| Product | 2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiazole-5-sulfonamide | HCID 61052651 | 67.7% |
Reaction Steps
Prepared by general procedure III from 2-chloro-thiazole-5-sulfonyl chloride (2.0 g, 9 mmol, example B.13, step 1) and 2-amino-2-methyl-1-propanol (0.95 g, 9 mmol) to give the title compound (1.65 g, 33%) as an off-white solid. MS (EI) 269.2[(M)+] and 271.2[(M+2)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07718661B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-f4f307edcfce43339eb3a4a50dd803f8 |
| Source note | uspto-grants-2010_05 |