HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiazole-5-sulfonamide → HCID 16738478, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiazole-5-sulfonamide | HCID 61052651 | — |
| Reactant | 3-Ethynyl-8-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine | HCID 86608011 | — |
| Product | HCID 16738478 | HCID 16738478 | — |
Reaction Steps
The title compound was prepared from 3-ethynyl-8-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine (example C.18) (354 mg, 1 mmol) and 2-chloro-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide (example B.19) (244 mg, 0.9 mmol) according to general procedure II. Obtained as a yellow solid (77 mg, 13%). MS (ISP) 589.3 [(M+H)+]; mp 202-203° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07718661B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-6356eddcd0a044c5b10c0a9cb04455fc |
| Source note | uspto-grants-2010_05 |