HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-fluorobenzylamine → N-[(2-chloro-4-fluorophenyl)methyl]-5-oxo-1-(phenylmethyl)prolinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-fluorobenzylamine | HCID 139909 | — |
| Reactant | N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(phenylmethyl)prolinamide | HCID 67461192 | — |
| Product | N-[(2-chloro-4-fluorophenyl)methyl]-5-oxo-1-(phenylmethyl)prolinamide | HCID 49864914 | — |
Reaction Steps
N-[(2-chloro-4-fluorophenyl)methyl]-5-oxo-1-(phenylmethyl)prolinamide was prepared in an analogous manner to that described for the synthesis of N-{[2-chloro-3-(trifluoromethyl)phenyl]methyl}-5-oxo-1-(phenylmethyl)prolinamide (Example 92) above but using [(2-chloro-4-fluorophenyl)methyl]amine in the place of {[2-chloro-3-(trifluoromethyl)phenyl]methyl}amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07718693B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-eb5b9a9d458a4bad8062d2b7917a63b6 |
| Source note | uspto-grants-2010_05 |