Octane → HCID 23650206, compound

Participants

Reaction Steps

Methyl ethyl ketone (7 mL) was added to 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one hydrate (258.17 mg, 0.71 mmol), and completely resolved under reflux by using oil bath. Then, tetrahydrofuran solution of L(+)-tartaric acid (6 mL, containing 0.77 mmol of tartaric acid) was added, and the heating of the oil bath was stopped. Then, n-octane (22 mL) was added to the mixture, solid was precipitated, and subsequently allowed to stand for about 13 hours and a half in the oil bath. The obtained solid was collected by filtration, washed by n-octane (small amount), dried under reduced pressure at 60° C., for about 5 hours to provide 283.86 mg of the title compound as white crystals.

Provenance & Evidence