Benzoic Acid → HCID 23650205, compound

Participants

Reaction Steps

Methyl ethyl ketone (6 mL) was added to 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one hydrate (253.6 mg, 0.70 mmol), and completely resolved under reflux by using oil bath. Then, tetrahydrofuran solution of benzoic acid (1 mL, containing 0.75 mmol of benzoic acid) was added, the heating of the oil bath was stopped, brought out from the oil bath, and subsequently allowed to stand at room temperature. The mixture returning to the room temperature was transferred to a weighing bottle and allowed to stand for about 15 hours in hood. The solid precipitated was dried under reduced pressure at 60° C. for about 4 hours to provide 249.81 mg of the title compound as slightly yellowish white crystals.

Provenance & Evidence