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HRID2238582

反应详情

EQUATION

反应方程式

HRID 2238582 的结构方程式

REACTANTS

反应物

2
结构：Cc1nc2c(O)cc(C(=O)N(C)C)cc2n1C
HCID53471016

4-Hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide

C12H15N3O2

结构：Fc1ccc2c(c1)OCCC2Cl
HCID68689066

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc2c(OC3CCOc4cc(F)ccc43)cc(C(=O)N(C)C)cc2n1C
HCID15980319

未命名化合物

收率 45%

PROCEDURE

实验过程

The title compound was prepared as a white solid in 45% yield (0.96 g) from 4-hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide (1.3 g, 5.5 mmol, WO 2004054984) and 4-chloro-7-fluorochromane (2.0 g, 11 mmol, STEP 2) by the same manner in STEP 1 of Example 1: