huagongshe.com
HRID2238583

反应详情

EQUATION

反应方程式

HRID 2238583 的结构方程式

REACTANTS

反应物

2
结构：Cc1nc2c(O)cc(C(=O)N(C)C)cc2n1C
HCID53471016

4-Hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide

C12H15N3O2

结构：Fc1cc(F)c2c(c1)OCCC2Cl
HCID68692125

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc2c(OC3CCOc4cc(F)cc(F)c43)cc(C(=O)N(C)C)cc2n1C
HCID16091076

未命名化合物

收率 49%

PROCEDURE

实验过程

The title compound was prepared as a white solid in 49% yield (0.12 g) from 4-hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide (0.14 g, 0.61 mmol, WO 2004054984) and 4-chloro-5,7-difluorochromane (0.15 g, 0.73 mmol, STEP 2) by the same manner in STEP 1 of Example 1: