huagongshe.com
HRID2238586

反应详情

EQUATION

反应方程式

HRID 2238586 的结构方程式

REACTANTS

反应物

2
反应SMILES：Cc1nc2c(O)cc(C(=O)N(C)C)cc2n1C
HCID53471016

4-Hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide

C12H15N3O2

反应SMILES：ClC1COCc2ccccc21
HCID68688409

未命名化合物

PRODUCTS

产物

1
反应SMILES：Cc1nc2c(OC3COCc4ccccc43)cc(C(=O)N(C)C)cc2n1C
HCID59303891

未命名化合物

收率 12%

PROCEDURE

实验过程

The title compound was prepared as a white solid in 12% yield (38 mg) from 4-hydroxy-N,N,1,2-tetramethyl-1H-benzimidazole-6-carboxamide (0.20 g, 0.85 mmol, WO 2004054984) and 4-chloro-3,4-dihydro-1H-isochromene (0.20 g, 1.2 mmol, STEP 1) by the same manner in STEP 1 of Example 1: