HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3S)-pyrrolidin-3-ol → HCID 59303887, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3S)-pyrrolidin-3-ol | HCID 2733874 | — |
| Reactant | 4-(3,4-Dihydro-2H-chromen-4-yloxy)-1,2-dimethyl-1H-benzimidazole-6-carboxylic acid | HCID 68689166 | — |
| Product | HCID 59303887 | HCID 59303887 | 25% |
Reaction Steps
The title compound was prepared as a white solid in 25% yield (30 mg) from 4-(3,4-dihydro-2H-chromen-4-yloxy)-1,2-dimethyl-1H-benzimidazole-6-carboxylic acid (100 mg, 0.30 mmol, STEP 2 of Example 11) and (S)-(+)-3-pyrrolidinol (77 mg, 0.63 mmol) by the same manner in STEP 3 of Example 11:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07718809B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-bfd4d1e1de5f4d8d867d9f54119d12e4 |
| Source note | uspto-grants-2010_05 |