Pyrrolidine → 4-[(5,7-Difluoro-3,4-dihydro-2H-chromen-4-yl)oxy]-1,2-dimethyl-6-(pyrrolidin-1-ylcarbonyl)-1H-benzimidazole

Participants

Reaction Steps

The title compound was prepared as a colorless amorphous in 39% yield (45 mg) from 4-[(5,7-difluoro-3,4-dihydro-2H-chromen-4-yl)oxy]-1,2-dimethyl-1H-benzimidazole-6-carboxylic acid (100 mg, 0.27 mmol, STEP 2 of Example 19) and pyrrolidine (38 mg, 0.53 mmol) by the same manner in STEP 3 of Example 11.

Provenance & Evidence