3-Benzyl-2,3-dihydro-1-benzofuran-5-yl-methanol → HCID 23081965, compound

HRID 2238605Notes

Reaction equation

HRID 2238605 reaction equation
[CH2:1]([CH:8]1[C:12]2[CH:13]=[C:14]([C:17]([O:19]CC)=O)[CH:15]=[CH:16][C:11]=2[O:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:22](C1C2C=C(CO)C=CC=2OC1)C1C=CC=CC=1>>[C:7]1([CH2:2][CH2:1][CH:8]2[C:12]3[CH:13]=[C:14]([CH2:17][OH:19])[CH:15]=[CH:16][C:11]=3[O:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:22]=1

Participants

3

Reactant 2

HCID 230819563-Benzyl-2,3-dihydro-1-benzofuran-5-yl-methanolHCID 23081994Ethyl 3-benzyl-2,3-dihydro-1-benzofuran-5-carboxylate

Product 1

HCID 23081965HCID 23081965, compound

Procedure

Analogously, starting from ethyl 3-benzyl-2,3-dihydro-1-benzofuran-5-carboxylate the 3-benzyl-2,3-dihydro-1-benzofuran-5-yl-methanol was obtained in 62% yield.

Workup

  1. customwas obtained in 62% yield

Sources & evidence

ORD record
ord-8d95ad2444724cbaac0632d8d1a4173f
Source dataset
uspto-grants-2010_05
Patent number
US07718815B2

Reaction notes

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