Diethyl Ether → HCID 747614, compound

HRID 2239207Notes

Reaction equation

HRID 2239207 reaction equation
[CH3:1][CH2:2][O:3][C:4]([CH2:6][C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8])=[O:5].[CH2:15](OCC)C>>[OH:8][C@:7]([C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)([CH3:15])[CH2:6][C:4]([O:3][CH2:2][CH3:1])=[O:5]

Participants

3

Reactant 2

HCID 3283Diethyl EtherHCID 7170Ethyl benzoylacetate

Product 1

HCID 747614HCID 747614, compound

Procedure

Ethyl benzoyl acetate (192 mg, 1 mmol) was added to diethylether (10 mL) and the solution applied to a sheet of filter paper. The solvent was left to evaporate. Yeast (10 g/mmol) was mixed with water (10 ml) and the resultant paste spread onto the filter paper and left for 24 h. The product was extracted from the yeast using ethyl acetate (2×30 mL). Evaporation under reduced pressure produced an essentially pure ethyl (R)-3-hydroxy-3-phenylbutanoate as an oil.

Workup

  1. waitThe solvent was left
  2. customto evaporate
  3. additionYeast (10 g/mmol) was mixed with water (10 ml)
  4. extractionThe product was extracted from the yeast
  5. customEvaporation under reduced pressure

Sources & evidence

ORD record
ord-29c3859426ad4b4f9533d4ef6497eeb5
Source dataset
uspto-grants-2010_05
Patent number
US07723065B2

Reaction notes

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