(6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-thioacetic acid S-pyridin-2-yl ester → 2-(6-Methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)-1-phenyl-ethanone

Participants

Reaction Steps

Prepared from (6-methyl-2-p-tolyl-imidazo[1,2-a]pyridin-3-yl)thioacetic acid S-pyridin-2-yl ester 1c and phenylmagnesium bromide using a similar procedure described above. 1H NMR (400 MHz, CDCl3) δ 2.26 (s, 3H), 2.37 (s, 3H), 4.64 (s, 2H), 7.00 (d, J=8.8 Hz, 1H), 7.21 (d, J=8.0 Hz, 2H), 7.41 (t, J=7.7 Hz, 2H), 7.52 (d, J=8.4 Hz, 2H), 7.58 (m, 3H), 7.96 (d, J=7.3 Hz, 2H). Mass spectrum m/e 341 (M+).

Provenance & Evidence