2,2-Diphenylethylamine → 2-tert-Butyl-4-[(2,2-diphenylethyl)amino]-5-phenylisothiazol-3(2H)-one 1,1-dioxide

Participants

Role	Name	HCID	Charge
Reactant	2,2-Diphenylethylamine	HCID 77575	—
Reactant	2-tert-Butyl-4-chloro-5-phenylisothiazol-3(2H)-one 1,1-dioxide	HCID 67242627	—
Product	2-tert-Butyl-4-[(2,2-diphenylethyl)amino]-5-phenylisothiazol-3(2H)-one 1,1-dioxide	HCID 11576225	—

Reaction Steps

The title compound was prepared from 2-tert-butyl-4-chloro-5-phenylisothiazol-3(2H)-one 1,1-dioxide and 2,2-diphenylethanamine in a similar manner as described for Example 1. 1H NMR (500 MHz CDCl3): δ 7.59-7.54 (m, 2H), 7.48-7.43 (m, 3H), 7.27 (t, 4H), 7.22 (t, 2H), 6.97 (d, 4H), 5.25 (t, 1H), 3.96 (t, 1H), 3.50 (dd, 2H), 1.70 (s, 9H); 13C NMR (125 MHz CDCl3): δ 159.6, 140.8, 135.0, 131.7, 129.9, 129.0, 128.0, 127.3, 125.3, 108.1, 61.7, 50.7, 48.3, 27.8; Mass Spectrum: M+H+ 461.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07723333B2
Source dataset	uspto-grants-2010_05
ORD ID	ord-c7b9282cac3f4e1bbbbc7c113c3da15e
Source note	uspto-grants-2010_05