Ethanol → HCID 58812098, compound

Participants

Reaction Steps

Ethanol (30 mL) and 10% palladium on carbon (0.439 g) were added to a hot solution of toluene-4-sulfonic acid 2-[3-(naphthalene-1-sulfonylmethyl)-4-nitro-phenoxy]-propyl ester (0.785 g, 1.41 mmol) in hot, anhydrous THF (40 mL). The reaction mixture was hydrogenated on the Parr apparatus for 2 hours (starting pressure of 43 psi). The reaction mixture was then filtered over Celite and concentrated. It was dried at 75° C. in vacuo for 20 minutes to yield toluene-4-sulfonic acid 3-[4-amino-3-(naphthalene-1-sulfonylmethyl)-phenoxy]-propyl ester as a brown-green semi-solid (0.627 g, 84.4%). Mass Spectrum (+EI, [M+H]+) m/z 526.

Provenance & Evidence