HCID 59128267, compound → HCID 178483161, compound

HRID 2240096Notes

Reaction equation

HRID 2240096 reaction equation
[CH3:1][N:2]([CH2:7][CH2:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][N:13]=[C:12]2[S:18]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:20])=[O:19])C(=O)OC.COC(=O)N(CCC1C=CC(N)=C(CS(C2C=CC=CC=2)(=O)=O)C=1)C>>[CH3:1][NH:2][CH2:7][CH2:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][N:13]=[C:12]2[S:18]([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:20])=[O:19]

Participants

3

Reactant 2

HCID 59128267HCID 59128267, compoundHCID 178502087HCID 178502087, compound

Product 1

HCID 178483161HCID 178483161, compound

Procedure

Methyl methyl{2-[3-(phenylsulfonyl)-1H-indazol-5-yl]ethyl}carbamate Using substantially the same procedure described in Example 171, step 3 and employing methyl(2-{4-amino-3-[(phenylsulfonyl)methyl]phenyl}ethyl)methylcarbamate (0.362 g, 1 mmol), the title compound was obtained as a white solid, (0.29 g, 78%). Mp: 145-147° C., MS (ES+): 374 (M+H)+ Step 6

Sources & evidence

ORD record
ord-1a824dc8fcc84e3d96039e83e9130035
Source dataset
uspto-grants-2010_05
Patent number
US07723329B2

Reaction notes

Loading…