HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 178524183, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Permanganate | HCID 516875 | — |
| Reactant | Sodium Bisulfite | HCID 23665763 | — |
| Reactant | HCID 178519381 | HCID 178519381 | — |
| Solvent | Acetonitrile--water (1/1) | HCID 18373917 | — |
| Product | HCID 178524183 | HCID 178524183 | 886.4% |
Reaction Steps
A mixture of 3-(naphthalene-1-sulfonyl)-1H-indazole-5-carbaldehyde (0.15 g, 0.44 mmoles) and KMnO4 (0.03 g, 0.29 moles) was stirred in CH3CN/H2O (4:1) for 1 hour. Reaction mixture was acidified with 2N HCl, stirred with saturated sodium bisulfite for 10 minutes, then extracted with EtOAc, dried over Na2SO4 and concentrated in vacuo to afford the title compound (0.13 g, 3.9 mmoles).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723329B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-98a450b6eb23408e903d4c58011f4c28 |
| Source note | uspto-grants-2010_05 |