HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-N-(5-methyl-isoxazol-3-yl)-acetamide → (R)-3-Hydroxy-1-[(5-methyl-isoxazol-3-ylcarbamoyl)-methyl]-1-azonia-bicyclo[2.2.2]octane bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-N-(5-methyl-isoxazol-3-yl)-acetamide | HCID 6485065 | — |
| Reactant | (R)-3-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide | HCID 86627857 | — |
| Product | (R)-3-Hydroxy-1-[(5-methyl-isoxazol-3-ylcarbamoyl)-methyl]-1-azonia-bicyclo[2.2.2]octane bromide | HCID 86627859 | — |
Reaction Steps
This compound is prepared analogously to (R)-3-hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide [Intermediate A] by substituting 2-bromo-N-isoxazol-3-yl-acetamide (in step Aii) with 2-bromo-N-(5-methyl-isoxazol-3-yl)-acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723356B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-fff3ee7212a840429a08b375d17288cc |
| Source note | uspto-grants-2010_05 |