HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-N-pyrimidin-4-yl-acetamide → (R)-3-Hydroxy-1-(pyrimidin-4-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-N-pyrimidin-4-yl-acetamide | HCID 44541927 | — |
| Reactant | (R)-3-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide | HCID 86627857 | — |
| Product | (R)-3-Hydroxy-1-(pyrimidin-4-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide | HCID 86627870 | — |
Reaction Steps
This compound was prepared by an analogous method to (R)-3-Hydroxy-1-(isoxazol-3-ylcarbamoylmethyl)-1-azonia-bicyclo[2.2.2]octane bromide (Intermediate A) by replacing 2-bromo-N-isoxazol-3-yl-acetamide (Ai) with 2-bromo-N-pyrimidin-4-yl-acetamide (Qi).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723356B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-5c8de105cf5247d7ab7e599308032165 |
| Source note | uspto-grants-2010_05 |