1-Isocyanato-3,5-dimethoxybenzene → HCID 178444872, compound

Participants

Reaction Steps

Into 50 ml round bottomed flask were added 6-(hexylamino)-1,3-benzothiazole-2-thiol (58.5 mg, 0.22 mmol), dichloromethane (10 ml) and 3,5-dimethoxyphenyl isocyanate (39.5 mg, 0.22 mmol). The reaction mixture was stirred 8 h, filtered, and the solid that was obtained was triturated with chloroform, followed with chloroform/methanol (9:1 mixture) to give 42 mg (43%) of the title compound. 1H NMR (DMSO-d6) δ=0.79 (t, 3H), 1.19 (br s, 5H), 1.40 (t, 2H), 3.28 (br s, 2H), 3.57 (t, 2H), 3.61 (s, 5H), 6.65 (d, 1H), 7.20 (d, 2H), 7.28 (d, 1H), 7.61 (d, 1H), 7.67 (s, 1H); ESIMS: m/z 444 (M−H).

Provenance & Evidence