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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2240355Generated: October 25, 2026

3-Hydroxypyridine → 6-Methyl-2-(pyridin-3-yloxy)-nicotinonitrile

https://huagongshe.com/reaction/2240355

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-HydroxypyridineHCID 7971—
Reactant2-Chloro-6-methylpyridine-3-carbonitrileHCID 520400—
Product6-Methyl-2-(pyridin-3-yloxy)-nicotinonitrileHCID 55207474—

Reaction Steps

2-chloro-6-methyl-nicotinonitrile was reacted with pyridin-3-ol according to the method of Example 85A to provide the title compound. MS (DCI/NH3) m/z 212 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723367B2
Source datasetuspto-grants-2010_05
ORD IDord-6b71787ef55842e899c6a0b73abb52b9
Source noteuspto-grants-2010_05