Thionyl Chloride → 3-(Azidomethyl)-2-ethylpyridine

HRID 2240375Notes

Reaction equation

[CH2:1]([C:3]1[C:8]([CH2:9]O)=[CH:7][CH:6]=[CH:5][N:4]=1)[CH3:2].S(Cl)(Cl)=O.[N-:15]=[N+:16]=[N-:17].[Na+]>>[N:15]([CH2:9][C:8]1[C:3]([CH2:1][CH3:2])=[N:4][CH:5]=[CH:6][CH:7]=1)=[N+:16]=[N-:17]

Participants

Reactant 3

HCID 24386Thionyl Chloride

HCID 33557Sodium Azide

HCID 19690951(2-Ethylpyridin-3-yl)methanol

Product 1

HCID 860822563-(Azidomethyl)-2-ethylpyridine

Procedure

The product of Example 124A, thionyl chloride and sodium azide were processed according to the method of Example 115A to provide the product. MS (ESI+) m/z 163 (M+H)+.

Workup

customto provide the product

Sources & evidence

ORD record: ord-c1add325b5ea47e8b79998ab3ff6eb8a
Source dataset: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07723367B2

Reaction notes

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