HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloronicotinonitrile → HCID 68585087, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloronicotinonitrile | HCID 81079 | — |
| Reactant | 3,4-Difluorobenzeneboronic acid | HCID 2734337 | — |
| Product | HCID 68585087 | HCID 68585087 | 77% |
Reaction Steps
Prepared in 77% yield from 2-chloro-3-cyanopyridine and 3,4-difluorophenylboronic acid according to the procedure described for Example 153A. 1H NMR (DMSO-d6) δ 7.62-7.71 (m, 2H), 7.74-7.79 (m, 1H), 7.95 (ddd, J=11.7, 7.8, 2.2 Hz, 1H), 8.46 (dd, J=7.8, 1.7 Hz, 1H) 8.94 (dd, J=5.1, 1.7 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07723367B2 |
| Source dataset | uspto-grants-2010_05 |
| ORD ID | ord-8448b45c4de3490ea7e6056b819efd42 |
| Source note | uspto-grants-2010_05 |