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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2240447Generated: October 26, 2026

2,3-Bis(trifluoromethyl)aniline → 1-(2,3-Bis(trifluoromethyl)phenyl)-3-(2-fluoropyridin-3-ylmethyl)thiourea

https://huagongshe.com/reaction/2240447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Bis(trifluoromethyl)anilineHCID 19980662—
Reactant(2-Fluoropyridin-3-yl)methanamineHCID 45079719—
Reactant2,3-Dichloro-1-fluorophenylisothiocyanateHCID 86603533—
Product1-(2,3-Bis(trifluoromethyl)phenyl)-3-(2-fluoropyridin-3-ylmethyl)thioureaHCID 8660353290%

Reaction Steps

Prepared in 90% yield from the product of Example 197A and the product of Example 193C according to the procedure described for the product of Example 192D and Example 192G.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07723367B2
Source datasetuspto-grants-2010_05
ORD IDord-afb3e0b2b3cb4d18a5991c57bb08e3b4
Source noteuspto-grants-2010_05