2-[3-(4-chlorophenyl)sulfonyl-2,5-dimethylindol-1-yl]acetic acid → 1H-Indole-1-acetic acid, 6-chloro-3-[(4-chlorophenyl)sulfonyl]-2-methyl-

HRID 2240548Notes

Reaction equation

HRID 2240548 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[C:17](C)[CH:18]=3)[N:13]([CH2:21][C:22]([OH:24])=[O:23])[C:12]=2[CH3:25])(=[O:10])=[O:9])=[CH:4][CH:3]=1.C(OC(=O)CN1C2C(=CC(C)=CC=2)C(S(C2C=CC([Cl:50])=CC=2)(=O)=O)=C1C)C>>[Cl:50][C:16]1[CH:15]=[C:14]2[C:19]([C:11]([S:8]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=3)(=[O:10])=[O:9])=[C:12]([CH3:25])[N:13]2[CH2:21][C:22]([OH:24])=[O:23])=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 104072752-[3-(4-chlorophenyl)sulfonyl-2,5-dimethylindol-1-yl]acetic acidHCID 68689500HCID 68689500, compound

Product 1

HCID 100694241H-Indole-1-acetic acid, 6-chloro-3-[(4-chlorophenyl)sulfonyl]-2-methyl-

Procedure

The title compound was prepared by the method of example 2 part (d) using the product from part (c).

Sources & evidence

ORD record
ord-203759d0deae47fc8276eee22a923a5e
Source dataset
uspto-grants-2010_05
Patent number
US07723373B2

Reaction notes

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