HCID 10095612, compound → HCID 10431493, compound

HRID 2240562Notes

Reaction equation

HRID 2240562 reaction equation
Cl[C:2]1[C:3](C#N)=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH2:11][C:12]([OH:14])=[O:13])[C:6]([CH3:15])=[C:5]2[S:16]([C:19]1[CH:24]=[CH:23][C:22]([Cl:25])=[CH:21][CH:20]=1)(=[O:18])=[O:17].ClC1C=CC(S([C:38]2C3C(=CC=CC=3NS(C)(=O)=O)[N:40](CC(O)=O)[C:39]=2C)(=O)=O)=CC=1.ClC1C=CC(SC2C3C(=CC=C(C)C=3)NC=2C)=CC=1>>[Cl:25][C:22]1[CH:21]=[CH:20][C:19]([S:16]([C:5]2[C:4]3[C:8](=[CH:9][CH:10]=[CH:2][C:3]=3[NH:40][CH2:39][CH3:38])[N:7]([CH2:11][C:12]([OH:14])=[O:13])[C:6]=2[CH3:15])(=[O:17])=[O:18])=[CH:24][CH:23]=1

Participants

4

Reactant 3

HCID 10095612HCID 10095612, compoundHCID 10387568HCID 10387568, compoundHCID 21077832HCID 21077832, compound

Product 1

HCID 10431493HCID 10431493, compound

Procedure

The title compound was prepared by the method of example 2 part (d) using the by product from example 22 part (a). Product was purified using reverse phase preparative HPLC.

Workup

  1. customProduct was purified

Sources & evidence

ORD record
ord-db6e9a42f91e49d4ae1ceb7897934afc
Source dataset
uspto-grants-2010_05
Patent number
US07723373B2

Reaction notes

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