1,2-Dichloroethane → HCID 11406298, compound

Participants

Reaction Steps

Benzyloxyamine was added to organic solvent dissolving 30 mg of 3-(1-benzyl-2-oxo-1,2,5,6-tetrahydro-pyridin-3-yl)-propionic acid (0.15 mM) prepared by above Example 12 in EDC. The resulting compound was purified by Silica gel column chromatography with ethylacetate/chloroform (1:1) solvent mixture as an eluant to give 41 mg of N-benzyloxy-3-(2-oxo-1-phenethyl-1,2,5,6-tetrahydro-pyridin-3-yl)-propionamide (g5) (yield: 75%).

Provenance & Evidence