HCID 68583344, compound → HCID 24996745, compound

Participants

Reaction Steps

5-{3-[2-(4-Bromo-benzyl)-4-(2,4-difluoro-phenyl)-imidazol-1-yl]-phenyl}-1,2,5-thiadiazolidine-3-one-1,1-dioxide (prepared according to general procedures A, J and C stepwise) (112 mg, 0.2 mmol) was treated as described in general procedure G using 3-(3,3-dimethyl-butylsulfanyl)phenylboronic acid (96 mg, 0.4 mmol, prepared according to general procedure I) to give 5-(3-{4-(2,4-difluoro-phenyl)-2-[3′-(3,3-dimethyl-butylsulfanyl)-biphenyl-4-ylmethyl]-imidazol-1-yl}-phenyl)-1,2,5-thiadiazolidine-3-one-1,1-dioxide.

Provenance & Evidence