4-tert-Butylphenylboronic acid → HCID 178440746, compound

Participants

Reaction Steps

2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-1H-imidazole (3.8 g, 10 mmol) was treated as described in general procedure G using 4-tert-butylphenylboronic acid (3.6 g, 20 mmol) to give 2-(4′-tert-butyl-biphenyl-4-ylmethyl)-4-(2,4-dichloro-phenyl)-1H-imidazole, which was treated as described in general procedure R using 1,4-diiodobenzene (13.2 g, 40 mmol) to give 2-(4′-tert-butyl-biphenyl-4-ylmethyl)-4-(2,4-dichloro-phenyl)-1-(4-iodo-phenyl)-1H-imidazole.

Provenance & Evidence