4-Cyclohexylbenzeneboronic acid → HCID 68582815, compound

Participants

Role	Name	HCID	Charge
Reactant	4-Cyclohexylbenzeneboronic acid	HCID 4589189	—
Reactant	{4-[2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenylamino}-acetic acid methyl ester	HCID 68583535	—
Product	HCID 68582815	HCID 68582815	—

Reaction Steps

{4-[2-(4-Bromo-benzyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenylamino}-acetic acid methyl ester (1.5 g, 2.7 mmol) was coupled with 4-cyclohexyl phenyl-boronic acid (700 m g, 3.4 mmol) according to general procedure G to give {4-[2-(4′-cyclohexyl-biphenyl-4-ylmethyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenylamino}acetic acid methyl ester.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07723369B2
Source dataset	uspto-grants-2010_05
ORD ID	ord-ad3b4e5a410945c59770efbff6b1a9d4
Source note	uspto-grants-2010_05