p-Fluoronitrobenzene → HCID 68585086, compound

HRID 2240730Notes

Reaction equation

HRID 2240730 reaction equation
[Br:1][C:2]1[CH:23]=[CH:22][C:5]([CH2:6][C:7]2[NH:8][CH:9]=[C:10]([C:12]3[CH:17]=[CH:16][C:15]([S:18]([CH3:21])(=[O:20])=[O:19])=[CH:14][CH:13]=3)[N:11]=2)=[CH:4][CH:3]=1.F[C:25]1[CH:30]=[CH:29][C:28]([N+:31]([O-:33])=[O:32])=[CH:27][CH:26]=1>>[Br:1][C:2]1[CH:23]=[CH:22][C:5]([CH2:6][C:7]2[N:8]([C:25]3[CH:30]=[CH:29][C:28]([N+:31]([O-:33])=[O:32])=[CH:27][CH:26]=3)[CH:9]=[C:10]([C:12]3[CH:17]=[CH:16][C:15]([S:18]([CH3:21])(=[O:19])=[O:20])=[CH:14][CH:13]=3)[N:11]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 9590p-FluoronitrobenzeneHCID 178504685HCID 178504685, compound

Product 1

HCID 68585086HCID 68585086, compound

Procedure

2-(4-Bromo-benzyl)-4-(4-methanesulfonyl-phenyl)-1H-imidazole (9.8 g, 25 mmol) was treated as described in general procedure B using 1-fluoro-4-nitrobenzene to give 2-(4-Bromo-benzyl)-1-(4-nitro-phenyl)-4-(4-methanesulfonyl-phenyl)-1H-imidazole.

Sources & evidence

ORD record
ord-17e52eca47d04b378d7075020e7d2237
Source dataset
uspto-grants-2010_05
Patent number
US07723369B2

Reaction notes

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